Evaluation of safety and efficacy of Mycoplasma hyopneumoniae bacterin (M+Pac) when administered as single and two dose under field conditions

Introduction Mycoplasma hyopneumoniae causes enzootic pneumonia that primarily affects growing pigs. Although the disease is nonfatal, it causes substantial losses attributable to reduced growth performance, increased susceptibility to secondary bacterial pneumonia, and potentiation of PRRSV-induced pneumonia.1, 2 Both cell-mediated and humoral immune responses appear to be important in providing protection against infection.3